MigraSoothe  FAQs

How do I buy MigraSoothe Products?

Sorry we do not sell Migrasoothe on this website. You can purchase products from Bespoke Biotics, or Amazon.

Why should I  add MigraSoothe 400Mg to my migraine treatment plan?

Migraines are a debilitating condition that affects millions of people worldwide. The symptoms of migraines can include intense headaches, nausea, and sensitivity to light and sound. While there are many different treatment options available for migraines, one that is often overlooked is the use of high dose riboflavin, also known as vitamin B2. In this article, we will discuss five reasons why you should consider taking high dose riboflavin as part of your migraine treatment plan.

MigraSoothe (Riboflavin) is a natural remedy

One of the main benefits of riboflavin is that it is a natural remedy. Unlike many prescription medications, MigraSoothe riboflavin is a vitamin that is found in a variety of foods, including eggs, milk, and leafy greens. Taking a high dose of MigraSoothe riboflavin as part of your migraine treatment plan means that you are using a natural remedy that is not likely to cause side effects.

Recommended by the NHS in the United Kingdom

The National Health Service (NHS) in the United Kingdom recognizes the potential benefits of riboflavin for migraine treatment and includes it as a recommended option in their guidelines. This is a strong indication of the effectiveness of MigraSoothe riboflavin as a treatment option, as the NHS is known for its rigorous standards when it comes to evidence-based healthcare.

Riboflavin has been shown to be effective in reducing migraines

Several studies have shown that riboflavin is effective in reducing the frequency and severity of migraines. In one study, participants who took high dose riboflavin (400mg per day) experienced a significant reduction in the number of migraines they had each month. Additionally, the participants reported that their migraines were less severe when they did occur.

MigraSoothe is well-tolerated

Another benefit of MigraSoothe riboflavin is that it is well-tolerated. Unlike some prescription medications, riboflavin is not associated with serious side effects. The most common side effects of riboflavin are mild and include nausea, diarrhea, and an upset stomach. These side effects are usually temporary and go away once the body becomes accustomed to the high dose of riboflavin.

Riboflavin can be taken with other medications

MigraSoothe riboflavin can be taken with other medications, making it a useful addition to your migraine treatment plan. If you are currently taking prescription medications for migraines, you can still take high dose riboflavin without any concerns about interactions. This makes it a great option for people who are looking for an additional treatment to help manage their migraines.

MigraSoothe is inexpensive

Lastly, MigraSoothe riboflavin is an inexpensive treatment option for migraines. MigraSoothe is  relatively inexpensive compared to many prescription medications which can costs tens or even hundreds of pounds.  MigraSoothe costs from 30p per day. 

Is MigraSoothe effective for chronic headaches?

Absolutely.  Migrasoothe may reduce the sensitivity of the brain to chronic headache triggers and be effective in relieving migraine pain.

How should I use MigraSoothe ?

Migrasoothe has been shown to be most effective by taking the capsules daily. We generally recommend taking it in the morning or afternoon rather than the eveningtime when you are winding down. 

Although some users see the benefits rapidly, for most beneficial results are usually encountered about 4 weeks of continued use. It is highly recommended to continue taking Migrasoothe for at least 4-6 months to experience the full beneficial effects.

What type of headaches does MigraSoothe help manage?

Migrasoothe may prove very beneficial in the management of migraine headaches and tension-type headaches. 

Type of migraine headaches that can be relieved with our migraine headache tablets include:

  • Intractable migraine, period and periodic migraine, hormonal migraine ease, ocular/optic migraine, familial migraine headache relief, hemiplegic migraine, plain hemiplegic migraine, ophthalmoplegic migraine (as define in UK migraine relief), episodic migraine, sinus related migraine, vestibular migraine, migraine with aura, chronic migraines, "silent" migraines, complex migraine tablets, abdominal migraine,  cyclical migraine. 

Using our natural migraine relief tablets in the long term you can work without any stress, pain and can focus more on your work.

How do I know which MigraSoothe is for me?

  • Neurologists often recommend MigraSoothe Original [Purple bottle] as a starting point for patients who are suffering from migraines. This product contains riboflavin (also known as vitamin B2) at a dosage of 400 mg. Riboflavin has been shown to be effective in reducing the frequency and intensity of migraines in some individuals. 
  • MigraSoothe + Herbs [Green Bottle] is a good option for those who are interested in using herbal supplements for migraine relief. This product combines the benefits of MigraSoothe Original with popular migraine treatments of feverfew and ginger.
  • For those who are already familiar with supplements and are looking to achieve the greatest benefit, MigraSoothe Pro Plus [Pink Bottle] is the most effective formula. This product contains extra vitamins, known as cofactors, as well as herbal supplements that have been shown to be beneficial for migraines. It also help boost mood which can be low for migraine sufferers.
  • It's important to note that the effectiveness of the product may vary for different individuals. It's always recommended to consult with your doctor or neurologist before taking any supplement.

Are there any side effects while using MigraSoothe?

Since riboflavin contains a unique fluorescent hue, most people will experience yellow-ish discolouration of your urine which is due to the excess Riboflavin vitamin B2 being excreted. This always occurs when taking vitamin B-containing supplements and should be of no concern. 

Some users report an energy boost. It is for this reason we do not recommend taking the supplement before bedtime.

On rare occasions, a very small number of users may experience diarrhoea or gastrointestinal disturbances as a side effect of using Riboflavin 400mg. However, these effects usually subside as the body becomes accustomed to the dosage. It is suggested to follow the acclimatization protocol below in such cases.

If you experience side effects

If you experience any side effects from taking MigraSoothe riboflavin, it's important to note that the supplement is made from natural food sources. However, it's possible for some users to experience unexpected effects due to their systems not being used to the energy or changes brought about by Riboflavin. This means that the body needs time to adjust to the new supplement, and the dosage may need to be gradually increased over time to reduce the likelihood of adverse side effects. In such cases, we recommend following an "acclimatization protocol." (This is a similar approach to the ones doctors sometimes use when giving patients new medicines).This protocol involves the following steps:

Supplement Acclimatisation Protocol

  • Start with a lower dose than the recommended amount: Take half of the capsule every three days. (You can open the vegetable capsule and reduce the content to approximately half.) Take the supplement with food and water,
  • Gradually increase the dosage: After 10 days or so, you can increase the dosage to a half capsule every two days.
  • Increase the dosage further: After another two weeks, you can gradually increase the dose to one full capsule every three days.
  • in 10 days or so Increase the dose yo a  full capsule  every two days 
  • After another 10 days reach the recommended daily dose in about 4-6 weeks time.

By following this acclimatization protocol, you can help your body gradually adjust to the supplement and reduce the likelihood of any adverse side effects.

Does the NHS (UK) really recommend ingredients used in MigraSoothe?

YES RIBOFLAVIN 400MG  - THE KEY PART OF OUR MIGRASOOTHE-Core products B I recommended by the NHS (the U.K.'s national health service) & NICE (the  UK's National Institute of Clinical Excellence)

For example see the leaflet 


or see


What if my symptoms are worse after taking MigraSoothe?

Why do some supplements cause a paradoxical reaction, where symptoms may worsen before they improve?

There are several reasons why certain supplements may cause a paradoxical reaction in some individuals, leading to a temporary worsening of symptoms before overall improvement:

  1. Detoxification process: Supplements with detoxification properties can cause a temporary increase in symptoms as the body works to eliminate toxins. This phenomenon, known as the "Herxheimer reaction," is characterized by flu-like symptoms, headaches, and fatigue. As the body continues to detoxify, these symptoms typically subside, and overall health may improve.
  2. Nutrient rebalancing: When starting a new supplement regimen, the body may need time to adjust to the increased levels of specific nutrients. This adjustment period can sometimes cause temporary side effects, such as digestive issues with magnesium supplements. However, these issues tend to resolve as the body becomes accustomed to the new nutrient levels.
  3. Overstimulation: Certain supplements, particularly those that impact the nervous system or hormone levels, can lead to overstimulation in some individuals. This can cause temporary worsening of symptoms, but may resolve as the body becomes accustomed to the supplement.

It's essential to remember that everyone's body is different, and individual reactions to supplements can vary. If you experience a paradoxical reaction to a supplement, consider follow our acclimatisation protocol by reducing your dose and building up more gradually or consulting with a healthcare professional to discuss the appropriate course of action. 

How soon does MigraSoothe work?

Though normal levels of B2  may be restored in as little as a week, Migrasoothe is most effective taken regularlyover at least  four months to see the full benefit.(as per NHSinformation)

Do I need my doctors approval to take MigraSoothe products?

Because Migrasoothe is a nutritional food supplement supplement, you don't need a prescription and it is deemed safe. 

However, it we always recommend you consult with your doctor or healthcare provider when taking any supplements. 

Do American /Canadian doctors recommend the ingredient of MigraSoothe?

Evidence points to a relationship between improperly functioning mitochondria organelles (the energy factories in each of our cells) and migraine. Therefore, studies have begun have investigated whether B2, which boosts mitochondria function, relieves migraine.

Several studies have now shown riboflavin’s efficacy in relieving headaches. As a result, the American Academy of Neurology and the American Headache Society and the Canadian Headache Society all recommend high dose Vitamin B2 as use in Migrasoothe key products. it is also recommended by  Agency for Healthcare Research and Quality (AHRQ) in the USA

My pee has gone yellow? Is it safe?

Riboflavin has a distinctive neon yellow colour. (In fact the word "flavin" part of the word derives from the Latin word “flavus”, meaning “yellow”). 

The yellow coloration of urine is normal when taking any type of riboflavin supplements. It is a result of the body excreting excess riboflavin. There is no need to be worried about this change in urine color.

I can't swallow capsules - can I open the capsule and take the powder?

if you are unable to swallow the riboflavin capsules, you can open them and mix the powder with food. However, riboflavin has a strong, bitter taste, so you may want to mix it with strongly flavoured foods or beverages to mask the taste.

Which global organisations recommend ingredient of MigraSoothe?

if you are unable to swallow the riboflavin capsules, you can open them and mix the powder with food. However, riboflavin has a strong, bitter taste, so you may want to mix it with strongly flavoured foods or beverages to mask the taste.

MigraSoothe  +HERBS

What is MigraSoothe +Herbs?

Migrasoothe +Herbs is an enhanced version of our original product. It contains two key natural botanical ingredients. Feverfew which has been used since the times of ancient Greece to treat chronic headache and migraine and Ginger which has been used in the Ayurvedic and Chinese medicine traditions to treat headaches and reduce inflammation.

Do any MigraSoothe products contain Butterbur?


Butterbur is a plant that has been traditionally used for medicinal purposes, including the treatment of allergies, asthma, and of course migraines. it is therefor popular with some migraine products.

 However, one concern is that butterbur contains pyrrolizidine alkaloids (PAs), which are toxic compounds that can cause liver damage and other serious health problems when consumed over a long period of time. In fact, long-term use of butterbur has been associated with hepatic issues, including liver damage and the development of liver tumors.

While some butterbur products are labeled as "PA-free," it is important to be aware that not all products may be free of these compounds, and it can be difficult to determine the levels of PAs in different butterbur products. Therefor we do not use it in any of our products.


MigraSoothe  +PRO

What is MigraSoothe Pro?

Migrasoothe Pro builds upon our product range by optimising Riboflavin 400mg dose 7 other ingredients: 

  • Vitamind B12 
  • Vitamin B6 
  • Folic Acid
  • Alpha Lipoic Acid (ALA) 
  • Feverfew
  • Ginger
  • Tryptophan

When should I use MigraSoothe Pro?

  • For most customers we recommend taking the Original formula or +herb formula together with coenzyme Q 10 and magnesium (eg see our triple pack)
  • After trying the original product, if you are after optimising even further, we can recommend the pro version.